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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIL4
All Species:
22.12
Human Site:
S374
Identified Species:
34.76
UniProt:
Q8WUA2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUA2
NP_624311.1
492
57225
S374
L
D
E
Q
A
E
D
S
K
S
S
H
S
H
T
Chimpanzee
Pan troglodytes
XP_527529
607
69328
S489
L
D
E
Q
A
E
D
S
K
S
S
H
S
H
T
Rhesus Macaque
Macaca mulatta
XP_001084421
492
57172
S374
L
D
E
Q
A
E
D
S
K
S
G
H
S
H
T
Dog
Lupus familis
XP_541147
492
57155
S374
L
D
E
Q
A
E
D
S
K
S
S
H
S
H
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXG3
492
57212
S374
L
D
E
Q
G
E
D
S
K
S
S
H
S
H
T
Rat
Rattus norvegicus
NP_001101927
357
40656
N240
A
D
I
K
P
P
E
N
V
L
F
V
C
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506397
487
56623
S370
L
D
G
E
R
E
E
S
R
A
H
H
S
Y
P
Chicken
Gallus gallus
XP_419663
478
55881
D360
E
K
V
K
P
K
Q
D
A
K
Y
D
L
V
L
Frog
Xenopus laevis
Q6GLX7
477
54856
A352
E
S
E
T
A
K
E
A
E
N
T
V
A
N
S
Zebra Danio
Brachydanio rerio
NP_001121802
454
52864
F336
G
K
Y
T
K
D
D
F
K
A
Y
E
K
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651291
653
75452
K409
R
R
T
R
S
K
E
K
D
E
K
S
V
Y
R
Honey Bee
Apis mellifera
XP_001121334
512
60307
K367
K
S
R
R
E
N
D
K
K
N
K
I
E
I
M
Nematode Worm
Caenorhab. elegans
NP_492343
427
50388
R310
D
N
V
L
I
D
D
R
R
I
H
V
D
F
S
Sea Urchin
Strong. purpuratus
XP_001192414
536
61906
S414
A
S
S
E
D
E
R
S
R
R
I
K
K
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q871A4
494
56481
R371
L
E
K
W
R
K
Y
R
D
E
D
V
E
W
R
Conservation
Percent
Protein Identity:
100
80.8
98.7
98.1
N.A.
96.7
71.9
N.A.
77
80.8
23.5
69.7
N.A.
42.4
48.6
47.5
51.1
Protein Similarity:
100
80.8
98.9
98.7
N.A.
98.1
72.3
N.A.
86.1
89
45.7
81
N.A.
55.9
65.8
65.6
65.4
P-Site Identity:
100
100
93.3
100
N.A.
93.3
6.6
N.A.
40
0
13.3
13.3
N.A.
0
13.3
6.6
13.3
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
26.6
N.A.
73.3
13.3
73.3
26.6
N.A.
33.3
26.6
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
60.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
34
0
0
7
7
14
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
7
47
0
0
7
14
54
7
14
0
7
7
7
7
0
% D
% Glu:
14
7
40
14
7
47
27
0
7
14
0
7
14
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
7
0
0
7
0
% F
% Gly:
7
0
7
0
7
0
0
0
0
0
7
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
14
40
0
34
0
% H
% Ile:
0
0
7
0
7
0
0
0
0
7
7
7
0
7
0
% I
% Lys:
7
14
7
14
7
27
0
14
47
7
14
7
14
14
0
% K
% Leu:
47
0
0
7
0
0
0
0
0
7
0
0
7
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
7
0
0
0
7
0
7
0
14
0
0
0
7
0
% N
% Pro:
0
0
0
0
14
7
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
0
0
34
0
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
7
7
7
14
14
0
7
14
20
7
0
0
0
0
14
% R
% Ser:
0
20
7
0
7
0
0
47
0
34
27
7
40
0
14
% S
% Thr:
0
0
7
14
0
0
0
0
0
0
7
0
0
0
34
% T
% Val:
0
0
14
0
0
0
0
0
7
0
0
27
7
7
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
0
7
0
0
0
7
0
0
0
14
0
0
14
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _